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精神分裂症中枢多巴胺功能及其相对代谢率的比较研究 被引量:6

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摘要 本文应用高效液相色谱(HPLC)对67例精神分裂症及10例健康对照组脑脊液中多巴(Dopa)、多巴胺(DA)、高香草酸(HVA)进行测试和比较,并以HVA/DA的比值作为DA相对代谢率。结果发现精神分裂症脑脊液中Dopa、DA、HVA与正常对照组无差异,而HVA/DA在精神分裂症中明显高于正常对照组,这一结果支持精神分裂症有多巴胺功能亢盛的观点。
出处 《临床精神医学杂志》 1993年第1期9-11,共3页 Journal of Clinical Psychiatry
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参考文献10

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二级参考文献1

  • 1B. Angrist,J. Rotrosen,S. Gershon. Differential effects of amphetamine and neuroleptics on negative Vs. positive symptoms in schizophrenia[J] 1980,Psychopharmacology(1):17~19

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