腹部手术后TPN治疗中的低血磷症及其防治

PREVENTION AND TREATMENT OF HYPOPHOSPHATEMIA IN PATIENT RECEIVING TPN FOLLOWING ABDOMINAL SURGERY

本文选择了16例腹部手术后TPN治疗的患者为观察对象,并随机分为补磷组(9例)及对照组(7例),连续测定血浆中磷水平和24小时尿中磷排出量。结果发现,对照组在TPN治疗后第4、7天血磷明显降低(P<0.01),既使无磷摄入,仍有相当的磷从尿排出;而补磷组则无低血磷现象发生。

Sixteen patients who received TPN treatment after abdominal surgery were studied. The group of phosphorus supplement (9 cases) and the control group (7 cases) were divided at random. After serially phosphorus in 24 hours, we found that the levels of serum phosphorus decreased on the fouth day (2.57±0.48mg/dl) and remained unchanged until the seventh day (2.60±0.27mg/dl) of TPN (P<0.01). Similary, the urinary excretion of phosphorus was also decreased. There was much urinary excretion of phosphorus, even when phosphate was not supplied, whereas no hypophosphatemia occurred in the group of phosphorus supplement.