摘要
白细胞具有趋边流动,粘附嵌墓及变形能力差等流变学特性,一方面可导致毛细胞血管中血流减慢或血流暂停,出现微循环紊乱,引起组织缺血缺氧;另一方面又释放溶酶体酶类,白三烯类物质及自由基等三种有害物质,造成微循环的进一步损害,组织营养进一步恶化。皮瓣移植前后由于外伤,烧伤及手术创伤等因素均可导致机体白细胞升高,使皮瓣微循环血流量逐渐减少,甚至出现皮瓣危象或皮瓣坏死。本文对上述有关问题进行了阐述,并为改善皮瓣微循环中的白细胞的流变行为,促进皮瓣好转,提出了一些见解。
The characteristics of leukocyte rheology are side-flow towards, adhesive and less deformability. Firstly, leukocytosis can result in the blood flow slower or no-reflow phenomenon in capillaries, then disorderly microcirculation and oxygen deficiency of tissue take place. Secondly,it also disperses three harmful factors: lysosome enzyme, LT and free radical. Thus microcirculation is further damaged, then the blood supply of tissue deteriorates. Leukocytosis can be seen pre-operation or post-operation due to injuries, burns and operation. The increasing number of leukocytes can make the blood supply of microcirculation decrease. Furthermore,skin flap failure or necrosis. For improving the leukocyte rheology in the microcirculation of skin flap, enhancing the blood supply of skin flap, there are six practical points.
出处
《中国烧伤创疡杂志》
1993年第1期12-15,62-63,共6页
The Chinese Journal of Burns Wounds & Surface Ulcers
