视网膜静脉阻塞患者高凝状态的检测分析

Analysis of the hypercoagulant state in patients with retinal vein occlusion

检测36例早期视网膜静脉阻塞(RVO)患者和20例正常人的血小板聚集与释放功能、血浆凝血因子和纤溶活性。结果,RVO患者的血小板聚集率、血浆纤维连接蛋白、因子Ⅷ相关抗原和纤溶酶原均高于正常人。表明RVO患者的血液呈高凝状态。这种血液凝固性异常可能在RVO的发生发展及其缺血性并发症上起重要作用。

The platelet aggregation and release reaction, the haemostatic factors and fibrinolytic activity were measured in 36 patients with early retinal vein occlusion (RVO) and 20 control subjects. The mean levels of platelet aggregation, plasma fibronection, factor Ⅷ antigen and plasminogen were significantly higher in the patients than in the controls. These findings showed that the blood hypercoagulant state was present in patients with RVO, and these abnormalities in blood coagulation could play an important role in the onset and development of RVO and its ischaemic complications.