肝病患者肝组织中丙型肝炎病毒感染的初步研究

Primary Study on Hepatitis C Virus Infection in Liver Tissues of Paticnts with Liver Discases

采用直接酶标记法对174例慢性肝炎、重症肝炎和肝癌组织中的HCV抗原进行了检测,HCV 抗原的检出率分别为10.71％、8.10％和2.68％。表明在我国慢性和重症肝病中存在HCV的感染。通过对HCV与HBV 感染关系的研究,发现肝内HBV 标志阳性和阴性者HCV抗原的检出率无明显差异,说明HCV感染与HBV感染之间似无明显关系。

Intrahepatic hepatitis C virus antigen (HCAg) was detected in liver tissue of 174 patients with chronic hepatitis (CH) ,severe hepatitis (SH) and hepatocellular -carcino ma (HCC) by direct enzyme-labelled technique. The detection rate was 10. 71%, 8. 10%, 2. 86% respectively.suggesting that there exist HCV infection in patients with chronic and severe liver diseases. The relationship between HCV and HBV infection was also studied and no significant difference was found in terms of HCAg detection rate between intrahepatic HBV positive and negative cases. It seems that HCV infection was unlikely related to HBV infection.