慢性阻塞性肺病患者右心收缩时间间期与肺血流动力学及右心功能关系的研究

Investigation on Right Ventricular Systolic Time Intervals and Their Rclationship with Pulmonary Hedodynamics and Right Ventricular Function in Patients with Chronic Obstructive Pulmonary Discasc

采用右心漂浮导管法测定了146例慢性阻塞性肺病(COPD)患者负荷试验前、后的右心收缩时间间期(RSTIs),分析其与肺血流动力学及右心功能的关系。结果:右心室后负荷指标肺动脉平均压(PAPm)与右室射血前期、右室射血时间和二者之比等项与RSTIs指标均有极显著相关性(P均<0.01),而右心功能指标与RSTIs指标无显著相关。提示RSTIs是反映COPD患者肺动脉压的良好指标,但用于观察右心功能的改变意义较小。

In the present study right ventricular systolic time intervals (RSTLs) were measured with the right cardial catheterization and their relationship with pulmonary hemo dynamics and right ventricular function was analysed both before and after the load test in patients with chronic obstructive pulmonary disease (COPD). The results showed that right ventricular after loaase (COPD). The results showed that right ventricular after load param eter pulmonary mean arterial pressure (PAPm) correlated significantly (P<0. 01) with RSTIs' parameters such as with the right ventricular pre-ejection period with the right ventricular ejection time and with their ratio . On the contrary,the right ventricular maximal pressure increasing rate showed no significant correlation with RSTIs. These results suggest that RSTIs can be used as indices to reflect the changcs of PAPm in COPD patients.but they will be of smaller value if used to observe the changes of right ventricular function.