维持性血液透析患者的丙型肝炎感染探讨

The Status of HCV Infection in Patients Receivcd Continual Hemodialysis or Kidncy Transplantation

对100例维持性血液透析及肾移植患者,进行了血清丙型肝炎抗体(抗 HCV)的检测,发现抗 HCV阳性率为41.0％,其中肾移植术后再透析者达56.52％。且透析时间越长、输血次数越多,受血量越大者,抗 HCV 阳性率越高(r=0.901,P<0.05;r=0.949.P<0.01)。提出尽快开展对献血员抗 HCV的检测,加强消毒隔离是降低丙型肝炎发生率的主要措施。

The antibody to HCV in the sera samples of 100 patients rcceived hemodial ysis or kidney transplantation was dctected. It was found that; 1)The rate of anti-HCV detec tion was 41% in these patients and 56. 52% in the patients received continual hemodialysisafter kidney transplantation;2)The duration of hemodialysis and the times (or the volumes) of recciving transfusion were positively correlated with the rate of anti-HCV detection (Υ = 0. 901,P<0. 05;Υ=0. 904,P<0. 01 .respectively). It was concluded that selection of anti-HCV negative blood donors and disinfection of hemodialysis units thoroughly are the main measures to prevent HCV infection in this special population.