黄芪刺五加治疗卵巢恶性肿瘤的免疫学研究

An Immunological Study of Trcatment of Ovarian Malignancies with A-AS

黄芪刺五加具有免疫增强作用。该文44例卵巢恶性肿瘤患者在化疗间歇期服黄芪刺五加,并测定其免疫功能。结果发现,用药后诱生α干扰素(IFN-α)和自然杀伤细胞(NK)活性水平逐渐增高。提示黄芪刺五加具有明显促进产生内源性IFN的作用,可对抗癌细胞和化疗药物的免疫抑制作用。

Astrogalus and acanthopanax senticocus(A-AS) have the capability to pro mote immune activities. 44 patients with ovarian malignancies were grouped and analysed in this study. A-AS were administered to the patients during the intervals of chemotherapy and the immune function of the patients was then determined. The levels of inducing IFN-α and NK activity in A-AS therapy group increased gradually,suggesting that A-AS have a stimu lating effect on the production of endogenous inducing IFN and may aid in resisting the im muno-α suppressive effects of cancer cells or chemotherapeutic agents.