呼吸道感染肺炎克雷白杆菌耐药性的研究

STUDY ON THE SENSITIVITY OF K.PNEUMONIAE ISOLATED FROM THE PATIENTS WITH RESPIRATORY TRACT INFECTION

6株从临床呼吸道感染患者分离的肺炎克雷白杆菌为多重耐药菌株,携带耐药质粒。经质粒提取、消除和转化试验证明,多重耐药肺炎克雷白杆菌的耐药基因,一些可定位于质粒DNA,另一些存在于细菌染色体上。

Six strains of K. pneumoniae isolated from the patients with respiratory tract infection, carring with plasids, are multiple drug resistance. Some drug-resistant genes locate in the plasmids, others in bacterial chromosome. These were proved by the experements of plasmid extraction, curing, and transformation.