健康人皮肤正常菌群的研究

Researchs on the SKin Microbial Flora in Healfty human

本研究对我国健康人皮肤正常菌群进行了探讨,发现在健康人前额皮肤上表皮葡萄球菌数为1.6×10~2～1.7×10~7/厘米~2,疮疤丙酸杆菌数为5.3×10~2～4.1×10~7/厘米~2,棒状杆菌数为1.31×10~2～4.1×10~4/厘米~2,真菌为0.17×10~2～6.1×10~3/厘米~2。在全皮标本中疮疱丙酸杆菌数为1.12×10~2～1.7×10~5/厘米~2,表皮葡萄球菌为1.36×10~2～3.9×10~2/厘米~2。表皮标本中,随年龄增加,表皮葡萄球菌有所减少,而金黄色葡萄球菌则增多。男女性皮肤正常菌群的比较中,表皮葡萄球菌、棒状杆菌、疮疱丙酸杆菌男性高于女性,而金黄色葡萄球菌、真菌却女性多于男性,但差异都不显著。全皮标本与表皮标本的比较中,表皮标本中表皮葡萄球菌、疮疱丙酸杆菌、金黄色葡萄球菌、棒状杆菌和真菌数都多于全皮标本,只是上述的后三种菌群的差异显著。

A study of normal dermal microbial flora of healthy human, it was found that on forehead the number of S. epidermidis was 1.6×10~2～1.7×10~7CFu/cm^2, that of P. acnes: 5.3×10~2～4.1×10~7CFu/cm^2, Carynebacteria: 1.31×10~2～4.1×10~3CFu/cm^2, Fungi: 0.17×10~2～6.1×10~2CFu/cm^2, and the total numbers on the whole skin specimen: P, acnes 1.12×10~2～1.7×10~7CFu/cm^2, S. epidermidis: 1.36×10~2～3.9×10~3CFu/cm^2. Among the cuticula specimen, that of S. epidermidiswas found to reduce in number with ageing, but S. aureuswas found to increase in numbers with ageing. Males were found to have more S. epidermidis. Corynebacteria' P. acres than females , and the latter were found to be inhabited more S. aurrenshan male, but the diversity of species was not nutable. Comparing with the specimens of whole skin, the numbers of S. epidemidis, P. acnes, S. anreue, Corynebactera Fungi on dermal specimens were found to be more than those from the speeiment of whole skin, but the diversity of species was found to be only notable in the last three mentioned.