解脲脲原体感染和不孕不育关系的研究

Study on the Relationship between the Infection of U. Urealyticum and Infertility

本文报道原因不明的不孕不育夫妇(甲组)2181例,解脲脲原体培养阳性1203例,阳性率55.16％。其中男性阳性率55.48％;女性为54.92％。正常生育夫妇(乙组)366例,阳性107例,阳性率为29.03％,其中男性18.93％,女性35.04％。两组比较,无论总阳性率,还是单独男性或女性,甲组均显著高于乙组(p<0.005)。经以强力霉素为主治疗后,转阴率达83.87％,其中妊娠390人,占38.65％。作者认为解脲脲原体感染和部分原因不明不孕不育是相关的。

U. Urealyticum isolation was taken in 2181 cases infertility. The positive isolations were observed in 692 of the 1260 females (54. 92％) and in 511 of the 921 males (55.48％) respectively, and the total positive rate was 55. 16％. The significant differences were found between the pasitive-isolation result of the infertility and that of the control group, the 366 normal fertility (P<0. 005). All cases of the ureaplasma infections were given the treatment with deoxycycline or erthromycin. There were 390 women in infertile couples becoming conceived and the eradication of the ureaplasmas was confirmed by the negative re-isola-tion in them. Based on the observation above, we suppose that there would be a correlation between the infection of U. urealyticum and some cases of the infertility.