高速投射物伤后肝脏早期损伤的观察

Early Liver Injury Following High Velocity Projectile Wounding to Dogs

用高速投射物致伤犬双后肢后,测定反映肝功状态的有关指标并观察肝超微结构。结果发现伤后24h肝损伤表现为:ATP及磷脂水平下降,MDA含量升高,血浆OCT活性增加及肝线粒体肿胀峭稀疏等。提示在高速投射物伤的早期救治阶段,应注意肝功的监测和维护。

Following high velocity projectile wound to dog legs, some indexes reflecting hepatic functions were measured. It was found that at 24 hr after wounding the ATP and phospholipid levels of the liver decreased, and that the OCT activity in serum and liver MDA content increased. The results revealed that the hepatic function impaired at 24hr after injury. It suggested that the hepatic function should be monitored and maintained even in the early period of high velocity projectile injury.