重症病毒性肝炎超微结构研究

AN ULTRASTRUCTURAL ATUDY OF THE LIVER WITH FULMINANT VIRAL HEPATITIS

应用扫描电镜技术和透射电镜技术,对41例重症病毒性肝炎患者肝组织进行超微结构观察。扫描电镜观察,肝细胞坏死分为三型,即虫蚀型坏死,厚膜型坏死和凝块型坏死。透射电镜观察,肝细胞坏死区除有淋巴细胞浸润外,还有较多单核细胞及少量浆细胞。提示其病变发生机制并不是单一的T细胞直接杀伤结果。

An ultrastruotuial observation for the study of the liver tissue in 41cases with fulminant viral hepatitis was made with the technique of SEM &TEM. with the observation of SFM, the necrosis of hepatic cells was prima-rily classified into three types, the worm-eating type, the thickening memb-rane type and the coagulated masg type. The TEM obseevation showed thatin the nelrotic region of liver cells. more monocytes and a small number ofplasma cells were found, including lymphocytes as well. This may sugget that themechanism of fulminant viral hepatitis is not noly the direct killing resthatultsby T-lymphocytes.