摘要
本文应用光镜及电镜观察了结扎大白鼠胆总管1、2、3、4周后肾脏的病理改变.结果表明:胆道梗阻一周即可引起肾小球滤过屏障损害、近曲小管上皮细胞变性.随胆道梗阻时间延长,病变逐渐加重,至第四周肾小球的全部超微结构明显受损,近曲小管上皮细胞明显变性及坏死。
The kidneys of the rats undergoing common bile duct ligation were studied with light and transmission electron microscope,respectively at 1、2、3 and 4 weeks postoperation.The results presented that the damage of glomerular filtration membrane had already taken place and,that the epithelial cells of the proximal tubule showed cloudy swelling at 1 week. The lesions of the kidney gradually became dramatic from 1 to 4 weeks. At last,all of the glomerular structuers were severely damaged and the epithelial cells of the proximal tubule appeared hydropic degeneration or necrosis.
出处
《农垦医学》
1991年第4期215-218,共4页
Journal of Nongken Medicine
关键词
梗阻性黄疸
肾脏
超微结构
obstructive jaundice
ren/kidney
ultrastructure
