高效液相色谱在甾体化合物11-β-羟化研究中的应用

The Application of HPLC to 11-β-Hydroxylation of Steroid

本文建立了用HPLC检测皮质醇中杂质的方法,优化了色谱条件,提高了方法的灵敏度和准确性,并应用于甾体化合物11-β-羟化研究。

The method is studied to test the impurities in cortisol with High performance Liquid Chro-matography (HpLC). As a tesult, the condition of HpLC is improved and the method whosesensitivity aud accuracy are increased has been applied to 11-β-hydroxylation of steroid.