摘要
体外实验观察肺表面活性物质主要成分卵、脑磷脂对石英毒作用下肺泡巨噬细胞的影响。结果表明:卵磷脂可以保护肺泡巨噬细胞,减轻石英的毒作用,脑磷脂则无此作用,进一步分析其机理,发现卵磷脂可以抑制肺泡巨噬细胞在石英毒作用下活性氧的产生,而脑磷脂则否。
The effects of phosphotidylcholine (PC) and phosphotidyletha-nolamine (PE) on alveolar macrophages treated with quartz in vitro were observed,The results showed that PC could protect alveolar macrophages from being damaged by quartz while PE failed to do so.Further observations suggested that PC can suppress the production of oxygen-free radicals by alveolar macrophages treated with quartz.
出处
《华中科技大学学报（医学版）》
CAS
CSCD
北大核心
1990年第S1期19-21,共3页
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
基金
七.五期间国家重点科技攻关项目
关键词
卵磷脂
脑磷脂
石英
巨噬细胞
phosphotidylcholine (PC)
phosphotidylethanolamine (PE) quartz
macrophages
