广州地区人群咽喉带菌情况及耐药性调查

Pathogenic Cocci Throat Carriers and Resistance to Drugs in Guangzhou Area

本文报道了在357例不同人群咽拭中分离培养出病原性球菌216株,总带菌率为60.5％,包括肺炎双球菌90株(25.2％)、甲型链球菌80株(22.4％)、乙型溶血性链菌球25株(7.0％)、致病性葡萄球菌21株(5.9％)。其中发热病儿和医护人员的带菌率明显高于其他人群(p<0.05及p<0.001)。药物敏感性试验表明:大多数菌株对常用抗菌药物仍较敏感,但有部分菌株对四环素、卡那霉素、红霉素、洁霉素、链霉素及新霉素等不同程度地产生了耐药性。文中分析了咽喉带菌在医院感染中可能成为内源性或外源性传染的意义,并提出对肺炎双球菌在广州地区呼吸道感染中的病原作用不宜忽视。

216 strains of pathogenic cocci were isolated and cultivated from throat swabs of 357 persons of various groups. The positive culture rate was totally 60.5% ,including 25.2% of Pneumococci, 22.4% of Viridans Streptococci, 7.0% of Hemolytic Streptococci and 5.9% of pathogenic Staphylococci. Children with fever, doctors and nurses showed higher rate than other persons of normal groups(p<0.005 and p<0.001). The results of antibacterial drug tests indicated that a small number of bacterial strains were found to be resistant to Kanamycin, Tetracy cline,Erythromycin Streptomycin and Neomycin,while most of them still susceptible to the daily used antibaterial drugs. The problem of the significance of throat carriers in the possible endogenous and exogenous infection in hospital was discussed. It is suggested that the pathogenic effect of Pneumococci in respiratory infection in Guangzhou area should not be neglected.