摘要
The amplitudes and latencies of auditory brainstem evoked response(ABR)were recorded at both high(50/s)and low(10/s)click rates as sound stimuli before andafter the guinea pigs were exposed to variant intensity noise.The maximum amplitude ofwave V increased significantly,but those of wave Ⅰ,Ⅲ,and Ⅳ decreased significantly afterexposure to 110 dB noise for 20 or 30 min.The wave Ⅴ latency recorded at 50/s clickrate was shorter in every group after exposure.The changes of wave V latency recordedat 10/s click rate were complex,it was shorter after exposure to 95 dB or 105 dB for 10min;no change was found after exposure to 110 dB for 10 min,but it was longer initiallyand then became shorter after exposure to 110 dB noise for 30 min.The difference valueof wave V latency from 10/s to 50/s was negatively correlated with the noise intensityand exposure time.The more intense noise stimuli and the longer time,the less the differ-ence value became.The results indicate that the auditory bralnstem center was affectedby intense noise,and it is helpful to use difference value of wave V latency to analysis thefunction of brainstem center after exposure to noise.
The amplitudes and latencies of auditory brainstem evoked response(ABR) were recorded at both high(50/s)and low(10/s)click rates as sound stimuli before and after the guinea pigs were exposed to variant intensity noise.The maximum amplitude of wave V increased significantly,but those of wave Ⅰ,Ⅲ,and Ⅳ decreased significantly after exposure to 110 dB noise for 20 or 30 min.The wave Ⅴ latency recorded at 50/s click rate was shorter in every group after exposure.The changes of wave V latency recorded at 10/s click rate were complex,it was shorter after exposure to 95 dB or 105 dB for 10 min;no change was found after exposure to 110 dB for 10 min,but it was longer initially and then became shorter after exposure to 110 dB noise for 30 min.The difference value of wave V latency from 10/s to 50/s was negatively correlated with the noise intensity and exposure time.The more intense noise stimuli and the longer time,the less the differ- ence value became.The results indicate that the auditory bralnstem center was affected by intense noise,and it is helpful to use difference value of wave V latency to analysis the function of brainstem center after exposure to noise.
