中药血液净化的研究及临床试用10例次疗效观察

Blood purification with traditional Chinese medicine:Summary of curative effect in 10 cases

血液透析为延长尿毒症病人的生命做出了重大贡献,但需要昂贵的血透机及净水系统。一般中、小医院难以开展,且血透机较大,不适于床边危重病人的就地抢救。当前不用特殊装置及透析液的血液净化方法——单纯超滤和连续性动静脉血液滤过(CAVH),虽然能保持体液恒定,但清除小分子毒素水平不足,为了弥补上述疗法的不足,适于中国国情,我院自1987年8月开始研究了中药血液净化及其床边装置。经高危险性终末期尿毒症病人10例(男9例、女1例)试用,本法经济、简便、安全,可根据病情行短时间的单纯超滤和长时间的 CAVH,还可清除体内部分中、小分子毒物。如处方及床边中药血液净化系统进一步完善、减少个体差异,有可能取代腹膜透析并应用于中、小医院甚至病人家庭。

Hemodialysis has made a great contribution to pro- longing the life of the patient suffering from uremia. However,it is difficult to develop hemodialysis in the middle or small sized hospitals because of the expensive equipment.The large size of the hemeodialysis equipment prevents the use of hemodialysis in patients who are criti- cally ill and need on-the-spot emergency treatment.Al- though the currently used blood purification without a special device and any dialysate,namely the so called' simple ultrafiltration'and centinuous arterio-venous hemofiltration(CAVH),can keep the body fluid stable,it can not achieve an adequate clearance of toxins of smsll molecular weight.In view of the above mentioned facts, we developed a blood purification system and a bed-side device with traditional Chinese medicine as dialysate. Since August,1987,this technique has been used in 10 crirically ill patients with terminal uremia(9,male and 1,female)and proved to be an inexpensive,simple, convenient and safe procedure,which can be used either for a short time(simple ultrafiltration)or for a long time (CAVH)according to the patient's condition.Also,it can eliminate some toxic substances of middle and small molecular weight.If the purification system can be fur- ther improved and the fluid component more reasonably adjusted to suit different patints,it may be possible to re- place peritoneal dialysis and used in the middle and small sized hospital,or even in the patient's home.For this rea- son,our new system is more suitable for the national con- dition of China.