食管癌体外照射结合高剂量率腔内后装放射治疗的探索

EXTERNAL BEAM COMBINED WITH HIGH-DOSE RATE INTRACAVITARY RADIOTHERAPY FOR ESOPHAGEAL CANCER. A PILOT STUDY

高剂量率腔内后装放射治疗(HDR),尚处于探索阶段。我院参考Hishikawa的方法,加以修改,试用体外放射治疗(ERT)结合HDR根治中晚期食管癌20例,本文报告方法与近期疗效。

From 1988 to 1989, 20 patients with locally advanced esophageal carcinoma were treated by external beam combined with high-dose rate intracavitary irradiation. Two types of 60Co pellets with 5 dose-reference points were used. 50-60Gy/5-6 wk was used in external irradiation and 8-18 Gy/2-4 F/2-3 wk was used in intracavitary treatment to a point 5 mm beneath the esophageal muco-sa. At the completion of treatment, 18 (90%) cases achieved complete response with peristalsis restored and 2 (10%) patients had complete response though with impaired peristalsis. During the limited follow-up, no patient developed recurrence. The complications are reported. We consider this method is rational and effective but further follow-up is needed.