肾小球在高钙低磷饲料致鸡痛风发生中的病理学分析

INDUCTION OF GOUT IN CHICKEN BY GIVING HIGH CALCIUM, LOW PHOSPORUS DIETS: PATHOLOGICAL ANALYSIS OF GLOMERULUS

本研究对高钙、低磷饲料人工诱发痛风鸡的肾脏进行了肾小球计数与病理变化观察,结果表明,高钙饲料能显著地引起鸡肾脏有效肾小球数量减少,并且还出现肾小球大小的改变与组织学病变.这些变化,可能是继发肾小管损伤后的结果.

An experiment was conducted to count the number of glomeruli and to observe the renal pathological change in the development of chicken gout induced by high dietary calcium and low dietary phosphorus. The result shows that: high dietary calcium caused a significant reduction in nephron number, a significant change in glomeruli size distributions and histologic change of glomeruli. These observations indicate that the glomeruli change may be the secondary injury following renal tubule injury.