不同病理类型的肺癌单放和化放综合治疗—附493例分析

COMBINED RADIOTHERAPY AND CHEMOTHERAPY FOR LUNG CANCERS - Analysis of 493 cases

1979年1月至1984年12月我科共收治经病理或细胞学证实的493例原发性支气管肺癌,分别采用单纯放疗和化疗加放疗综合治疗两组,分析如下:

493 patients with lung carcinoma proved by pathology or cytology (273-squamous cell carcinoma) (55.2%), 101 small cell lung carcinoma(SCLC) (20.5 %) , 92 adenocarcinoma (18.7%) and 27 other types (5.5%)were treated from 1979 to 1984. 288 patients were treated by radiotherapy alone, 205 patients by chemotherapy combined with radiotherapy.SCLC gave 1, 2 and 5 year survival rates of 51.2%, 22.6% and 3.6% with the median survival of 13 months in the chemo-radiotherapy group. In the radiotherapy alone group, the l year survival was 29.4%, and none survived the second year. The median survival time was 6 months in the radiotherapy alone group. The results speak favorably for the chemo-radiotherapy regime and one should be cautious in instituting surgery. For squamous cell carcinoma, combined therapy was not superior to radiotherapy alone. For adenocarcinoma combined chemo-radiotherapy gave a median survival of 2 months, longer than radiotherapy alone (8 months)