用Franz接触电极导管记录犬心内膜单相动作电位

USING FRANZ'S CONTACT ELECTRODE CATHETER TO RECORD MONOPHASIC ACTION POTENTIALS FROM CANINE ENDOCARDIUM

作者首次采用Franz接触电极导管记录了犬心内膜单相动作电位(MAP),观察了心内膜MAP的形态特点,并对163个单位电生理参数进行了统计学处理,结果表明:单相动作电位振幅(MAPA)44.01±6.99mv,Vmax8.20±2.86v/s,动作电位时间(APD_(50))154.58±28235ms,APD_(90)215.49±34.96ms,心率(HR)134.73土17.04次/分。并对APD作了校正。本实验结果为心内膜的研究提供了基础电生理资料。

The authors employed for the first time Franz’s contact electrode catheter to record the monophasic action potentials(MAP)from left endocardium of canines and analysed the configuration of MAP from the endocardium. The electrophysiological parameters were as follows: monophasic action potential amplitude(MAPA)44.01±6.99mv, the maximum depolarization rate of phase 0(Vmax)8,20±2.86v/s and MAP duration. at 50%, 90% repolarization 154.58±28.35, 215.49±34.96ms, respectively. In order to avoid the effect of different heart rates on MAP duration, APDs were corrected.