血清病对动脉壁结缔组织基质代谢影响——超微定量分析

The Immunological Injury from Serum Sickness on Aortic Connective tissue Components

钌红染色,电镜观察免疫损伤对动脉壁结缔组织代谢的影响。结果表明:重复注射大剂量抗原刺激动脉壁平滑肌细胞增生和蛋白多糖、胶原、弹性纤维的合成,使动脉壁结缔组织成份增加。这种结缔组织成份增加与动脉壁平滑肌细胞增生、细胞器肥大的形态学改变一致。

Changes of aortic proteoglycan,collagen and elastic fibers following immunological injury were studied quantitatively and qualitatively by electron mi- croscope.The results showed that repeated intravenous injections of bovine serum albumin in rabbits activated synthesis of collagen,elastic fibers and proteoglycan in aortic wall.The increase of connective tissue components was coincident with morphological changes of smooth muscle cell.