光学活性倍半萜类化合物R-(-)-α-姜黄烯,(-)-姜烯衍生物的合成

THE SYNTHESIS OF OPTICAL-ACTIVE SESQUITERENES R-(-)-α-CURCUMENE, SUBSTITUTED ZINGIBERENES AND THE EXPLORATION OF THEIR ANTIFERTILITY EFFECTS

本文叙述了具有光学活性的倍半萜类化合物R-(-)-a-姜黄烯及具有不同取代基的姜烯类化合物的合成,其巾五个未见文献报道,同时对合成中所用的Stork环合反应进行了较深入的探索。

The synthesis of optical-active sesquiterpens, R-(-)-α-Curcumene(Ⅰ) and a series of substituted (-)-Zingiberene (Ⅲ)_(a-e) (R=-CH_3, -C_2H_5,C_3H_7, -CH(CH_3)_2, -C_4H_9), (-)-β-isopropyl-Sesquiphellandrene (Ⅲ_f) was described in this article.