幽门弯曲菌与常见胃病关系及尿素酶速诊价值

Relation of Campylobacter pyloridis to Common Gastri Diseases and Valuation of Rapid Urease Test

我们于1989年1月至5月应用组织学 MB 染色、光镜下观察并作尿素酶速诊试验检查124例胃、十二指肠活检标本。MB 染色镜下观察和尿素酶速诊试验的 CP 检出率分别是67.0%和63.7%。尿素酶速诊试验敏感性91.6%,特异性92.3%。MB 染色检查,CP 在消化性溃疡,慢性浅表性胃炎,慢性萎缩性胃炎,十二指肠球炎和胆汁返流性胃炎的检出率分别为80.0%,69.4%,70.5%,61.5%和11.1%。残胃炎1/3阳性,胃癌三例均阴性。组织学上炎症程度重,CP 感染较明显。镜下粘膜红斑征的 CP 检出率高于其它表现。

From Jan to May,1989,124 cases of gastroduodenal diseases were examined with fiberoptic gastroscopy.All biopsies were stained with MB stain and examined under light microscope,and by rapid urease test. The detection rates of Campylobacter pyloridis(CP)with MB stain and Rapid Urease test were 67.0% and 63.7% respectively.The Rapid Urease test had a sensitivity of 91.6% and a specificity of 92.3%.In peptic ulcer,superficial gastritis,atrophic gastritis,duodenitis and bile reflux gastritis,the detection rates of CP with MB stain were 80.0%,69.4%, 70.5%,61.5% and 11.1%,respectively.Of the 3 cases of remanent gastritis, one showed positive findings while no CP was found in the 3 cases of gastric carcinoma.The severity of inflammation was positively correlated with the number of CP.The detection fete of CP in the gastric erythema appearance by gastroscopy was higher than othere.