参七散对2型糖尿病并脂代谢紊乱的影响

Effects of Shenqi Powder on Lipid Metabolism in Patients with Type 2 Diabetes Mellitus

目的:观察参七散对2型糖尿病并脂代谢紊乱的影响。方法:将148例2型糖尿病肥胖患者分为2组。治疗组予参七散(组成:西洋参、三七)治疗,每天1剂,水煎服。对照组给予非诺贝特胶囊治疗。均治疗8周。观察血清甘油三酯(TG)、糖化血红蛋白(HbA1c)、空腹血糖(FBG)及餐后2h血糖(P2hBG)、体重指数(BM)I。结果:2组治疗后在FBG、P2hBG、TG、BMI等方面均有明显改善,与治疗前比较,差异有显著性或非常显著性意义(P<0.05,P<0.01);2组治疗8周后,治疗组FBG、P2hBG、BMI 3项指标与对照组比较,差异均有显著性意义(P<0.05)。结论:参七散治疗2型糖尿病疗效肯定。

Objective： To investigate the effect of Shenqi Powder on lipid metabolism in patients with type 2 diabetes mellitus. Methods： One hundred and forty-eight patients with type 2 diabetes mellitus were divided into Shenqi Powder group（n=72） and Fenofibrate dispersible tablets group（n=76）. Shenqi Powder is composed of Radix Panacis Quinquefolii and Radix Notoginseng, and was used in decoction, one dose per day. All patients were treated for 8 weeks. Triglyceride（TG）, Hemoglobin A, glycosylated hemoglobin（HbAlc）, fasting blood glucose（FBG）, 2-hour postprandial blood glucose（P2hBG）, and body mass index（BMI） were observed. Results： FBG, P2hBG, TG and BMI in both groups were improved after treatment（P 〈 0.05compared with those before treatment）.The differences of FBG, P2hBG and BMI between the two groups after treatment were significant （P 〈 0.05）. Conclusion： Shenqi Powder can effectively decrease BMI, TG and blood glucose levels.