过敏性紫癜患儿血、尿β_2-mG检测及临床意义

Test and clinical implication of blood and urine β_2-mG in children with Henoch-Schonlein purpura

目的探讨过敏性紫癜患儿血、尿β2-mG检测的临床意义。方法选择HSP患儿30例为A组,30例HSPN患儿为B组,30例健康儿童为C组,入院后2 d内取血液及尿液标本应用放射免疫分析法检测其β2-mG水平。结果 A组及B组患儿血β2-mG及尿β2-mG均较C组显著升高(P<0.05)。B组患儿血β2-mG为(3.29±0.62)mg/L,尿β2-mG为(0.97±0.19)mg/L,均明显高于A组(P<0.05)。结论过敏性紫癜患儿伴有血、尿β2-mG水平升高,伴有肾功能损伤的患儿更加明显。

Objective To investigate the clinical implication of blood and urine β2-mG in children with HSP.Methods 30 children with HSP were chosen as A group,30 children with HSPN as B group,30 healthy children as group C.Blood and urine samples were taken within 2 days after admission for the test of β2-mG using radioimmunoassay method.Results The blood β2-mG and urinary β2-mG of A group and B group were significantly higher than those in C group（P 0.05）.The blood β2-mG and urinary β2-mG of group B were（3.29 ± 0.62） mg/L and（0.97 ± 0.19） mg/L,they were significantly higher than those in B group（P 0.05）.Conclusion Blood and urine β2-mG levels were increased in children with HSP,they were much more higher in children associated with renal damage.