摘要
目的 利用超声生物显微镜（UBM）观察非穿透性小梁手术（NPTS）联合SKGEL植入后房水引流途径的变化、滤过道的改变及并发症的发生情况.方法 回顾性分析2009年9月～2010年8月,26例（38眼）开角型青光眼（POAG）患者行NPTS联合SKGEL植入.术后1周～18个月,利用UBM观察滤过泡、巩膜池、剩余小梁膜、植入物的变化及脉络膜脱离等并发症情况.对前部巩膜池的体积进行统计学分析.结果 术后1周,5例患者发现有脉络膜浅脱离,术后2周恢复.手术部位均形成巩膜池.随访期间,前部巩膜池逐渐缩小,差异具有显著性.结论 UBM适合NPTS术后观察,滤过道重塑是长期过程,SKGEL胶可以短期抑制纤维化.前部巩膜池是维持NPTS手术效果的关键,但体积逐渐缩小预示NPTS的长期效果难以预计.
Objective To evaluate the effect of non-penetrating trabecular surgery（NPTS） with SKGEL inplant on patients with primary open-angle glaueoma（ POAG） ,to observe the changes of drainage passway of aqueous humor and postoperative filtration area, and complications with ultrasound biomieroseopy （ UBM ）. Methods The clinical data of 26 patients（38 eyes} with POAG performed NPTS with SKGEL implant was analyzed retrospectively between September 1,2009 and August 31,2010. SKGEL was applied in patients with POAG. With UBM the following parameters were assessed ：conjunctival blet） appearance, condition of suprascleral aqueous lake, the thickness of residual trabeculcorheal membrane,condition of the plants and choroidal detachment. Results Choroidal detachment was dignosised in 5 patients with POAG at 1 week and disappeared at 2 week after the operation. The anterior aqueous lakes contracted gradually and the margin of liquid lakes was irregular gradually. During 1-18 months after the operation the area of anterior aqueous lakes contracted significantly. Conclusions UBM was suited for postoperative long-term follow-up. SKGEL could suppress fibrosis in short-term. The anterior aqueous lake is the key for success of NPTS. Due to long-time sclera remodeling after surgery,the contracting gradually of suprascleral aqueous lakes may denote that it is hard to predict the long-time effectiveness of NPTS.
出处
《潍坊医学院学报》
2011年第3期193-196,共4页
Acta Academiae Medicinae Weifang
