宫颈环切术围术期联合疗法预防并发症疗效观察

Integrated therapy during the perioperational period for the prevention of complications of loop electrosurgical ex- cision procedure

目的 观察围手术期联合疗法防治宫颈环形电切术并发症的效果.方法 治疗组45例术前1天顿服甲硝唑2 g,术前0.5-1 h口服莫西沙星0.4 g及云南白药胶囊2粒,术毕宫颈创面喷涂云南白药粉剂,术后口服云南白药及莫西沙星2 d,术后第3 d阴道放置聚甲酚磺醛栓.对照组44例术前无处理,术毕创面填塞明胶海绵,术后抗菌药物治疗.比较两组术中出血量、术后创面感染、脱痂期出血及宫颈外观.结果 治疗组术中出血量（4.4±2.4）g较对照组（7.5±3.3）g减少,差异有统计学意义.对照组发生3例脱痂期宫颈创面出血量多,9.1%创面感染,6.8%宫颈管肉芽增生,治疗组未发生上述并发症.结论 围手术期联合疗法可有效防治宫颈环形电切术并发症.

Objective To assess the effectiveness of integrated therapy during the perioperational period for the prevention of complications associated with loop electrosurgical excision procedure （LEEP）. Methods In the treatment group （n = 45 ）, antimicrobial agents and Yunnan Baiyao capsule were used before LEEP; Yunnan Baiyao powder was in- suffiatod at the site of LEEP incision when the operation was finished. Moxifloxacin and Yunnan Baiyao capsule were used continuously after the operation for 2 days. Policresulen suppository was put in vagina once every other day for 18 times be- ginning at the third day after operation. No such treatment was given to the control group （ n = 44）. Results The a- mount of blood loss in treatment group was （4.4 ± 2.4 ） g, and （7.5 ± 3.3 ） g in the control group. The difference was significant. In the control group, there were 3 cases of exfoliating hemorrhage, 4 cases of incision infection, and 3 cases of cervical granulation tissue hyperplasia; no these complications were found in the treatment group. Conclusion Integrated therapy during the perioperational period can effectively reduce complications associated with LEEP.