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腹腔引流液中炎性细胞因子检测对术后早期炎性肠梗阻诊断的研究 被引量:5

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摘要 目的探讨腹部手术后腹腔引流液中炎性细胞因子作为预测和诊断术后早期炎性肠梗阻的意义和可行性。方法22例腹部手术后早期炎性肠梗阻患者(肠梗阻组)和10例腹部手术后正常恢复患者(对照组),于术后1、5d检测腹腔引流液和血清中自细胞介素(IL)-6、IL-8、IL-10、肿瘤坏死因子(TNF)-α和C反应蛋白(CRP)水平。结果肠梗阻组术后1、5d腹腔引流液中IL-6、IL-8、IL-10、TNF-α和CRP水平均显著高于同期对照组,并随治疗呈持续性下降态势(P〈0.05);肠梗阻组术后1、5d腹腔引流液中各炎性细胞因子水平变化较血清中变化敏感,出现较早且幅度较大(P〈0.05)。结论腹腔引流液中炎性细胞因子是反映腹腔内炎性反应的敏感指标,有助于发现术后早期炎性肠梗阻,避免严重后果。
出处 《中国医师进修杂志》 2011年第32期52-54,共3页 Chinese Journal of Postgraduates of Medicine
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