MicroRNA与胶质瘤

MiRNA and Gliomas

已经有越来越多的证据表明基因组的非编码序列的转录对于生命活动具有重要的意义,相对于蛋白编码序列以及各种小分子RNA,miRNA的研究还仅仅处于起步阶段,其功能与调控机制仍有待进一步研究。本文对目前关于miRNA与胶质瘤关系的研究进展进行综述,认为miRNA可能为胶质瘤诊断和治疗提供新依据和靶点。

There has been increasing evidence that non-coding genome sequence of the transcriptional activity of life is significant.Relative to the protein coding sequence and a variety of small molecule RNA,miRNA research still only in its infancy.Its function and regulation need further study.In this paper,the current relationship between the gliomas and the miRNA was reviewed.With the research progress,we hope that miRNA may provide new cancer diagnosis and treatment basis and targets.