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重组腺病毒载体介导外源性XIAP抑制听皮层GABA能神经元凋亡与老年性聋相关性研究进展 被引量：1

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摘要 老年性聋是一类随年龄增长而出现的以双耳进行性高频听力下降为主要表现的慢性退行性疾病。研究表明,大于65岁的老人中,40%以上受老年性聋困扰[1,2]。随着中国逐步进入老龄化社会,老年性聋因严重影响老年人的生活质量而受到社会关注。目前,老年性聋的发病机制并不十分清楚,但研究发现外周听觉系统和听觉中枢功能失调共同参与了老年性聋的发病,其中听觉中枢神经细胞凋亡引起听觉中枢功能障碍是老年性聋患者听力下降、
作者 胡玥 姬长友 陈继川
机构地区 第三军医大学大坪医院野战外科研究所耳鼻咽喉-头颈外科
出处 《听力学及言语疾病杂志》 CAS CSCD 北大核心 2011年第6期579-581,共3页 Journal of Audiology and Speech Pathology
基金 国家自然科学基金资助(30872861)
关键词 老年性聋 腺病毒载体介导 神经元凋亡 GABA能 XIAP 相关性 听皮层 外源性
分类号 R764.436 [医药卫生—耳鼻咽喉科]
  • 相关文献

参考文献30

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二级参考文献66

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共引文献8

同被引文献21

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听力学及言语疾病杂志
2011年 第6期

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