从兽用生物制品企业角度看我国SPF鸡质量控制现状

Veterinary Bioproducts Enterprises' View On Current Situation of the Quality Control of SPF Chicken in China

SPF鸡和鸡胚是兽用生物制品生产和检验环节的主要原材料,直接影响到产品质量和检验结果,2010年版《中国兽药典》(三部)附录《生产、检验用动物标准》明确要求,用于禽类制品毒种制备与鉴定、病毒活疫苗生产与检验、灭活疫苗检验的鸡和鸡胚应符合国家无特定病原体(SPF级)动物标准。SPF鸡的质量控制包括遗传、微生物、环境和营养四个方面,本文主要从兽用生物制品生产企业的角度,分析国内SPF鸡质控指标,结合禽用活疫苗生产和检验实践,提出对SPF鸡质量控制的思考和建议。

Results of quality control test and even the quality of the products are directly affected by SPF chickens and SPF embryos ,which are the main raw materials of production and quality inspection in veterinary biological products. Chickens and embryos must meet the national SPF animal standards requirement from the animal standards in production and inspection in the veterinary pharmacopoeia of the People＇s Republic of China （2010） , in the seed lots and biological products preparation and quality inspection. The quality control of SPF chicken includes four tests, namely inheritance, microorganism , environment and nutrition respectively. The current standards for quality control of SPF chickens are reviewed in the perspective of bioproducts enterprises. In this article, critical ideas and practical proposals for quality control of SPF chickens based on the practice of production and quality inspect in poultry live vaccine are presented.