摘要
中国糖尿病患病率成倍增长,近几年血糖波动逐渐为人们所重视。波动性高血糖相对于持续性高血糖更能增加糖尿病患者发生并发症的危险性,尤其是对心血管内皮细胞的损害。血糖波动通过氧化应激等机制损伤内皮细胞参与糖尿病并发症的进展。因此,对血糖波动的正确认识、评价和积极控制将有助于减缓糖尿病并发症的发生,改善患者预后。
With the prevalence of diabetes in China,the blood glucose fluctuations of diabetics are attracting more concern in recent years.Compared with sustained high blood glucose the blood glucose fluctuation increases the incidence of diatetes complications more,especially cardiovascular endothelial dysfunction.Blood glucose fluctuation participate in the development of diabetic complications through oxidative stress mechanism which injures endothelial cells.Therefore,a correct understanding and evaluation of blood glucose fluctuations and prompt control will help reduce the incidence of diabetic complications and improve the prognosis.
出处
《医学综述》
2011年第22期3446-3449,共4页
Medical Recapitulate
关键词
血糖波动
心血管内皮
氧化应激
Blood glucose fluctuation
Cardiovascular endothelium
Oxidative stress
