宁夏某非疫区肾综合征出血热的流行病学调查分析

An Epidemiological Analysis of the Epidemic Hemorrhagic Fever in a Non-infected Area of Ningxia

目的基于宁夏某非疫区发生1例肾综合征出血热病例,故对该地部分人群及宿主动物肾综合征出血热感染情况进行调查。方法采集患者急性期和恢复期血液标本;在患者现居住地及周边地区随机调查16～60周岁人群,采集血液标本;居民区及野外进行鼠种构成、密度调查,并采集鼠血、鼠肺标本。对人、鼠标本分别进行出血热抗体或抗原检测。结果患者急性期血清肾综合征出血热病毒IgM抗体阳性,恢复期血清特异性IgG抗体阳性,为实验室确诊病例。患者居住地96份人群血清肾综合征出血热IgG抗体均为阴性。居民区鼠密度为2.10%,优势鼠种为小家鼠;野外鼠密度为2.40%,优势鼠种为小家鼠。81份鼠肺、鼠血标本中,鼠肺出血热抗原、鼠血出血热IgG抗体均为阴性。结论此次调查工作虽未找到流行性出血热传染源,但病例为确诊病例,需加强宿主动物监测工作和宣传教育工作,探索病例发生的原因,有效防控疫情。

Objective To investigate epidemic situation of the epidemic hemorrhagic fever in a non-infected area of Ningxia.Methods Blood samples were collected in patients on acute and recovery stage.The persons aged 15 to 60 years old who living in the surrounding areas of patients were randomly investigated and taken blood samples.Samples from rodents were collected.The species,density and virus rates of rodents were analyzed.Results The blood samples of patient was positive.The blood samples of healthy persons were negative.All of the lung tissue and blood samples from rodents were negative.The rodents density was 2.10% in the residential area,while the field was 2.40%.Musmusculus were the predominant rodents in both the residential area and the field.Conclusion The investigation did not found infection source,but cases was confirmed cases with the epidemic hemorrhagic fever.Host animal monitoring and propaganda education on the epidemic hemorrhagic fever need to be further strengthened and improved.