抗菌肽对肉仔鸡生产性能及免疫功能的影响

Effect of Antimicrobial Peptides on Growth Performance and Immune Function of Broilers

试验旨在探讨抗菌肽对肉仔鸡生产性能及免疫器官指数的影响。选择96只1日龄AA肉仔鸡，随机分成4个日粮处理组，每个日粮处理组分4个重复，每个重复6只鸡。第1组为对照组，饲喂基础日粮，第2、3、4组分别在日粮中添加100、300、600mg／kg抗菌肽，试验期21天。结果表明：日粮中添加600mg／kg水平的抗菌肽能显著提高21天AA肉仔鸡的平均日增重（P〈0．05），添加300mg／kg、600mg／kg水平的抗菌肽能使其料重比显著降低（P〈0．05）。21日龄时抗菌肽处理组的胸腺指数和脾脏指数与对照组比较没有差异（P〉0．05）；而600mg／kg抗菌肽组的法氏囊指数显著高于对照组（P〈0．05）。添加抗菌肽对肉仔鸡的IgM、溶菌酶及白蛋白含量没有显著影响（P〉0．05）。但300mg／kg及600mg／kg抗菌肽组的IgG水平显著高于对照组（P〈0．05）。这表明抗菌肽能显著提高肉鸡的生产性能，改善免疫功能。

An experiment was conducted to study the effects of different doses of antimicrobial peptides on growth performance and immune function of broilers. A total of 96, 1 d old AA broilers were randomly allotted to four dietary treatments （6 birds per pen with 4 pens per treatment）. The control group were fed with the basal diet alone, the other treatments fed the basal diet supplemented with 100,300,600 mg/kg antimierobial peptides, respectively. The experiment period were 21d. The results showed that supplementing 600 mg/kg antimicrobial peptides significandy increased average daily gain （ADG） of 21d AA broilers （ P 〈 0.05 ）, and supplementing 300 mg/kg or 600mg/kg antimicrobial peptides significantly decreased feed -gain ratio（F/G） of21d AA broilers（ P 〈 0.05 ）. There was no difference in thymus index and spleen index of 21d AA broilers between control group and antimicrobial peptides treated groups （ P 〉 0.05 ）. However, supplementing 600 mg/kg antimicrobial peptides significantly increased bursa of fabricius index of 21d AA broilers （P 〈 0.05 ）. Supplementing antimicrobial peptides had no significant effect in IgM content, lysozyme and albumin level of21d AA broilers （P 〉 0.05）. But, supplementing 600 mg/kg antimicrobial peptides significantly increased IgG level of 21d AA broilers （P 〈0.05）. The results indicated that the antimicrobial could improve the growth performance and immune function of broilers.