广西侗族人群ABO及Rh血型分布调查分析

The investigation and analysis of ABO and Rh blood type distribution in Guangxi Dong nationality

目的:了解广西侗族人群ABO及Rh血型分布及基因频率。方法:对检测人群严格入选标准,随机抽取1927例非血缘关系的广西侗族人群进行ABO及Rh血型鉴定和分析。结果:ABO血型分布特征:O>B>A>AB;基因频率p(A)=0.1556、q(B)=0.1920、r(O)=0.6524;Rh(D)阴性率为0.052%,d基因频率0.0228。Rh发现8种表型,以CCDee频率最高(65.28%),未发现CCDEE表型。组合体基因频率以CDe(0.8080)为最高。结论:广西侗族人群ABO、Rh血型分布符合国内南方少数民族的分布特征,但Rh阴性比例明显低于汉族人群。

Objective：To survey ABO and Rh blood type distribution and gene frequency in Guangxi Dong nationality.Method：1,927 unrelated people of Guangxi Dong nationality were randomly collected and the ABO/Rh blood type were identified and analyzed.Result：The feature of ABO blood type distribution was： OBAAB;The gene frequency was p（A）=0.1556、q（B）=0.1920、r（O）=0.6524;Rh（D） negative rate was 0.052%,d gene frequency was 0.0228.Eight phenotypes were found in Rh blood type,CCDee frequency was highest（65.28%）,CCDEE phenotype was not found.CDe（0.8080） was highest in the combination of gene frequency.Conclusion：The distribution of ABO and Rh blood type in Guangxi Dong nationality is accord with the feature of distribution in China southern minority nationalities,but Rh negative ratio is obviously lower than Han nationality.