人类免疫缺陷病毒相关性神经认知功能损害
被引量:4
摘要
中枢神经系统(CNS)是HIV最常攻击的部位。在20世纪80年代艾滋病流行初期,人们已经注意到HIV感染导致的神经认知功能损害,如HIV相关性痴呆等。近15年来,随着大量相关研究的展开和高效抗反转录病毒治疗(HAART)的广泛应用,人们对HIV相关性神经认知功能损害的认识不断提高。本文将从临床角度总结近期HIV相关性神经认知功能损害领域的进展,以协助我国的临床医生了解和掌握相关的知识。
出处
《中华传染病杂志》
CAS
CSCD
北大核心
2011年第10期625-628,共4页
Chinese Journal of Infectious Diseases
参考文献30
-
1Snider WD, Simpson DM, Nielsen S, et al. Neurological complications of acquired immune deficiency syndrome: analysis of 50 patients. Ann Neurol, 1983,14:403-418.
-
2Grant I, Atkinson JH, Hesselink JR, et al. Evidence for early central nervous system involvement in the acquired immunodeficiency syndrome (AIDS) and other humanimmunodeficiency virus (HIV) infections. Studies with neuropsychologie testing and magnetic resonance imaging. Ann Intern Med, 1987,107:828-836.
-
3Zhang F, Dou Z, Ma Y, et al. Five year outcomes of the China National Free Antiretroviral Treatment Program. Ann Intern Med, 2009,151:241-52.
-
4Antinori A, Arendt G, Becker JT, et al. Updated research nosology for HIV associated neurocognitive disorders. Neurology, 2007,69 : 1789-1799.
-
5McArthur JC, Steiner J, Sacktor N, et al. Human immunodeficiency virus associated neurocognitive disorders: Mind the gap. Ann Neurol, 2010,67:699-714.
-
6Heaton RK, Cysique LA, Jin H, et al. Neurobehavioraleffects of human immunodeficiency virus infection among former plasma donors in rural China. J Neurovirol, 2008,14:536-549.
-
7Spector SA, Singh KK, Gupta S, et al. APOE epsilon4 and MBL-2O/O genotypes are associated with neurocognitiveimpairment in HIV-infected plasma donors. AIDS, 2010,24: 1471-1479.
-
8I.etendre SL, Ellis RJ, Ances BM, et al. Neurologie complications of HIV disease and their treatment. Top HIV Med, 2010,18:45-55.
-
9Vago L, Bonetto S, Nebuloni M,et al. Pathological findings in the central nervous system of AIDS patients on assumedantiretroviral therapeutic regimens: retrospective study of 1597 autopsies. AIDS, 2002 ,16 :1925-1928.
-
10Thompson KA, McArthur JC, Wesselingh Sir. Correlation between neurological progression and astrocyte apoptosis inHIV-associated dementia. Ann Neurol, 2001, 49:745-752.
同被引文献70
-
1黄世敬,危剑安,曹惠云,孙利民,游秀珍,苏小游,黄霞珍,苏诚练,许铣,李国勤,刘国,王健,吕维柏,于智敏,那奥米,夏邬丽.中医辨证治疗艾滋病729例临床观察[J].中医杂志,2004,45(9):680-682. 被引量:27
-
2王爱霞,王福生,王清玥,王健,冯铁建,卢洪洲,孙洪清,孙永涛,叶寒辉,李太生,李兴旺,刘正印,邢玉兰,何云,汪宁,吴昊,吴南屏,张福杰,周曾全,宫恩聪,赵红心,赵敏,唐小平,徐莲芝,徐小元,曹韵贞,康来仪,蒋岩,蔡卫平,樊庆泊,潘孝彰.艾滋病诊疗指南[J].中华传染病杂志,2006,24(2):133-144. 被引量:631
-
3邱红,谢世平,郭选贤.HIV/AIDS患者274例中医证候流行病学分布[J].郑州大学学报(医学版),2007,42(2):363-364. 被引量:34
-
4Singer [J, Valdes-Sueiras M, Commins D, et al. Neurologic pres- entations of AIDS[J]. Neurol Clin, 2010,28 (1) : 253 - 275.
-
5Ghafouri M, Amini S, Khalili K, et al. HIV-1 associated demen- tia: symptoms and causes[J]. Retrovirology, 2006 , 3 : 28.
-
6Sehouten J, Cinque P, Gisslen M,et al. HIV 1 infection and cog- nltive impairment in the cART-era a review[J]. J Acquir Immune Defic Syndr,2011,25(5) ;561-75.
-
7Tozzi V, Balestra P, Salvatori MF, et al. Changes in Cognition During Antiretroviral Therapy Comparison of 2 Different Rank- ing Systems to Measure Antiretroviral Drug Efficacy on HIV-As- sociated Neurocognitive Disorders[J]. J Acquir Immune Defic Syn- dr,2009, 52(1), 56-63.
-
8Giunta B, Ehrhart J, Obregon DF, etal. : Antiretroviral medica- tions disrupt microglial phagocytosis of b-amyloid and increase its production by neurons: Implications for HIV-associated neurocog- nitive disorders[J]. Mol Brain. 2011 ,4(1) :23.
-
9Heaton RK, Cysique LA, Jin H, et al. Neurobehavioral effects of HIV infection among former plasma donors in rural China: Neu- rohehavioral effects of HIV in rural China[J]. J Neurovirol,2008, 14(6) :536-549.
-
10Keblesh JP, Reiner BC, Liu J, et al. Pathogenesis of Human Im- munodeficiency Virus Type-1 ( HIV-1 )-Associated Dementia= Role of Voltage-Gated Potassium Channels[J]. Retrovirology , 2008,2(1) :1-10.
引证文献4
-
1黄英秀,周海卫,曾辉,赵红心.HIV相关神经认知障碍的影响因素[J].中国艾滋病性病,2013,19(9):700-704. 被引量:4
-
2叶显芬,陈子蓉,赵婷婷.广西地区艾滋病患者认知功能初步调查[J].重庆医学,2015,44(12):1673-1675. 被引量:3
-
3孙娜,范颂,郭亚收,刘启玲,李星慧,张荣强.HIV相关神经认知障碍患者脑组织基因表达谱的变化及生物信息学分析[J].中华疾病控制杂志,2017,21(12):1277-1281. 被引量:1
-
4张雪,蒋自强,陈丽华,孙燕,杨萱,王双利,安永辉,张晓华,焦敏,张静.186例艾滋病痴呆复合征中医证型分布特点[J].中国中医药信息杂志,2017,24(3):14-17. 被引量:1
二级引证文献9
-
1梁发俊,李华钢.28例以认知障碍为首发症状的HIV/AIDS病人回顾分析[J].中国艾滋病性病,2020,0(2):205-206.
-
2苏武锦,陈悦,黄茜.南宁地区2006~2015年无偿献血者HIV阳性的分布特征[J].重庆医学,2016,45(29):4110-4112. 被引量:10
-
3杨馨,杨峥嵘.HIV相关神经认知功能障碍的研究进展[J].国际流行病学传染病学杂志,2016,0(5):333-337. 被引量:6
-
4杨永锐,冯煜,沈九成,沈凌.抗病毒治疗艾滋病患者HIV相关性痴呆量表测试分析[J].昆明医科大学学报,2017,38(12):125-129. 被引量:2
-
5孙娜,范颂,郭亚收,刘启玲,李星慧,张荣强.HIV相关神经认知障碍患者脑组织基因表达谱的变化及生物信息学分析[J].中华疾病控制杂志,2017,21(12):1277-1281. 被引量:1
-
6吴少天,邱荃,李亮平,徐立然.艾滋病中医病因病机研究进展[J].中医研究,2019,32(6):77-78. 被引量:10
-
7汪颖,李朋,王博,刘丕楠.中枢性PNET患者基因表达谱变化及生物信息学分析[J].医学研究杂志,2020,49(3):30-34. 被引量:1
-
8林兆煜,张波婷,刘佳佳,姜敏,陶鹏飞,楼金成,李惠琴,钱俊.盐酸多奈哌齐治疗艾滋病痴呆综合征认知功能疗效分析[J].中国艾滋病性病,2021,27(3):229-232. 被引量:3
-
9熊文琴,刘芳,喻行莉,祝静,陈燕华.中国HIV相关神经认知障碍患病率的Meta分析[J].中国艾滋病性病,2021,27(5):494-498. 被引量:6
-
1吴卫星,马贤凯.人免疫缺陷病毒核心蛋白的研究进展[J].中华实验和临床病毒学杂志,1992,6(3):317-321.
-
2王文昭,赵瑛,仓世文,赵忠新,邵福源.人类免疫缺陷病毒相关性痴呆一例[J].上海医学,2005,28(7):588-588.
-
3武有聪,白丽,袁有华,刘奇.人类免疫缺陷病毒相关性口腔念珠菌的药物敏感性分析[J].中国新药与临床杂志,2008,27(9):687-690. 被引量:4
-
4姜拥军,康辉,王亚男.人类免疫缺陷病毒逆转录酶活性测定[J].中国医科大学学报,2000,29(S1):80-81.
-
5廖万清,顾菊林.医学真菌学研究的现状与展望[J].国际皮肤性病学杂志,2006,32(2):65-66. 被引量:2
-
6吉昌华,苏成芝.人类免疫缺陷病毒调控蛋白研究进展[J].国外医学(微生物学分册),1992,15(2):57-60.
-
7党灵,袁双凤,赵鲜丽.AIDS患者亲属的心理状况调查[J].中国误诊学杂志,2005,5(13):2565-2565.
-
8高楠竣,陈英杰,李雪涛,孔维云,周轶平.人胸腺组织原代培养细胞与人类免疫缺陷病毒间的相互作用[J].中国组织工程研究与临床康复,2011,15(50):9344-9347.
-
9闫秋林,热依拉.艾滋病病人的护理[J].中华当代医学,2004,2(9):122-123.
-
10谭伟.人类免疫缺陷病毒基因组中抑制自身结构蛋白表达的序列成分[J].生物工程进展,1994,14(3):31-35.