以环形疹为主要表现的二期梅毒误诊1例

A Case of Easily Misdiagnosed Annular Rash of Secondary Syphilis

患者男,26岁。阴茎、阴囊环形皮损,表面扁平,上覆少许鳞屑,瘙痒2月。外院以"湿疹和皮炎"治疗,无好转。皮损组织病理示:角化亢进及角化不全,棘层肥厚,上皮突延长,真皮浅层及血管周围有大量淋巴细胞、浆细胞浸润。RPR1:160(+),TPHA(+)。诊断:二期梅毒。予以苄星青霉素240万U治疗,皮损消退。现在随访中。

A 26-year-old male had presented itching annular rashes which covered by few scales on the scrotum and penis for two months. Histological examination ： hyperkeratosis, parakeratosis, and acanthosis, epidermal ridge extension, lymphocytes and plasma cells infiltrated superficial dermis and perivascular space. Syphilis serology： TPHA（ ＋ ） ,RPR 1： 160（ ＋ ）. Diagnosis： secondary syphilis.