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胰岛素抵抗:结核感染新的标志物

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摘要 当前控制结核病流行的措施主要集中于活动期结核患者的快速诊断及治疗方面。虽然这一策略取得了巨大成功,但是肺结核仍然是威胁全球公共卫生安全的一大隐患。这就要求我们尽可能地去寻找引发结核感染的风险因素及早期标志物,以便早期预防、早期诊断并治疗。胰岛素不仅在调节细胞代谢方面发挥关键作用,并且能够影响其吞噬结核分枝杆菌的能力。胰岛素抵抗伴发于诸多疾病进程中,但是至今还没有评估胰岛素抵抗与结核感染风险关系的研究。我们认为,胰岛素抵抗可以增加结核感染风险,并且可以作为评判其发展为活动期结核的一种标志物。
出处 《医学争鸣》 CAS 北大核心 2011年第5期25-28,共4页 Negative
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