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血管生成素-1在缺血性脑损伤中的作用研究进展 被引量:8

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摘要 血管生成素(Ang)在缺血性脑损伤中的作用越来越引起关注,尤其是Ang-1,不仅通过加强内皮细胞间的紧密连结,降低血管通透性,维持血脑屏障完整性;并能促进缺血脑组织周围侧支循环形成、延缓血管退化,稳定血管;还能直接抑制神经细胞凋亡,保护缺血半暗带神经元。本文就Ang-1的生物学特性,在缺血性脑损伤中的表达及其作用机制研究进展予以综述。
出处 《国际神经病学神经外科学杂志》 2011年第5期496-500,共5页 Journal of International Neurology and Neurosurgery
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