某铀矿632例工作人员淋巴细胞染色体畸变情况调查

Study on Lymphocyte Chromosome Aberration of 632 Workers at Uranium Mines

按照《中华人民共和国职业病防治法》及《放射工作人员职业健康管理办法》,以性别、年龄、工种和工龄来分类,对某铀矿632名铀矿工染色体畸变情况进行调查。调查结果表明,不同性别、工龄、工种工作人员染色单体畸变率、染色体畸变率、染色体型畸变细胞率和阳性超标率差异均不显著,然而,采矿组和水冶组工作人员阳性超标率较高;不同年龄组之间的差异显著,其中26～35岁工作人员染色体畸变率和阳性超标率最高;年龄和工种交互作用对染色单体畸变率的影响差异显著;工种和工龄交互作用对染色体畸变率和染色体型畸变细胞率的影响差异极显著;其它交互作用对染色单体畸变率、染色体畸变率、染色体型畸变细胞率和阳性超标率影响差异不显著。

In accordance with the ＂Occupational Disease Prevention Law of the PRC＂ and ＂Occupational Health Management for Radiation Workers＂,632 uranium miners were sorted by gender,age,type of work and length of service to examine their chromosome aberration.The findings showed that there was no statistically significant of chromatid aberration rate,chromosome aberration rate,chromosome aberration cells rate and the positive rate among different gender,length of service,types of work.However,the rate of positive in the mining group and the hydrometallurgy group was higher;there was statistically significant differences between different age groups,chromosome aberration rate and the positive rate were the highest in 26 to 35 years group.There was statistically significant of chromatid aberration rate by the interaction of age and type of work;and there were statistically significant of chromosome aberration rate and chromosome aberration cells rate by the interaction of type of work and length of service;There were not statistically significant chromatid aberration rate,chromosome aberration rate,chromosome aberration cells rate and the positive rate by other interaction.