多孔TCP陶瓷支架的制备及其性能研究

Preparation and characterization of porous Tri-Calcium Phosphate ceramic scaffold

目的生物陶瓷作为骨修复材料已经得到广泛使用，研究多孔磷酸三钙（TcP）生物陶瓷的制备方法及性能。方法以羟基磷灰石（HA）为原料，通过加入钙磷生物玻璃调节钙磷比，在高温加热过程中实现多孔TCP陶瓷支架的制备。结果经测试用这种方法制得的TCP支架比单纯用TCP粉末制得的TCP支架具有更高的机械强度，其强度可达9．11MPa。结论磷酸三钙具有良好的生物相容性和生物可降解性，在生理环境中可被逐步分解、吸收，诱发骨的生长，最终使骨缺损部位完全被新生的骨组织所取代。

Objective Bio-ceramics has been widely utilized as a common type of bone repair material. The research was designed to focus on preparation and characterization of porous TCP. Methods By using hydroxyapatite （HA） as the raw materials, and adding calcium phosphate bio-glass to adjust the ratio between calcium and phosphate, in order to achieve making porous TCP bio-ceramic seaffolds during high temperature heating process. Results Test results showed that by applying this method, TCP seaffohts had signific.antly higher mechanical strength then those were made from powdered TCP, and its compressive strength reaehed 9.11 MPa. Conclusion Tri-Calcium Phosphate （TCP） has excellent biocompatibility and it is also biodegradable. In the physiological environment, it is able to be gradually decomposed, absorbed and to promote bone growth ultimately, it is capable of replacing the damaged bone components with brand new bone tissues.