模拟微重力对机体内皮细胞、血小板功能的影响

Influences of simulated microgravity on human endothelial cells and platelets

重力状态的改变将引起机体一系列生理机能的异常，如心血管系统中血液的重新分布、骨骼系统中骨质破坏的增加、造血系统中造血组织的减少等。人类登月计划的顺利实现以及空间站的成功建立，为研究微重力状态下机体生理功能的改变开启了新的篇章。随着模拟微重力仪的研发更足使这一领域出现了飞速的发展，但关于微重力状态下机体凝血功能的改变还有待进一步研究，特别是对于当今这个出血和血栓性疾病高发的时代更是刻不容缓。这将为预防航天员出血疾病的发生或血栓的形成提供一定的参考，同时将进一步推动我国航天事业的发展。

The change of gravity causes a series of physiological dysfunctions, such as redistribution of blood, destruction of skeleton, reduction of hemopoietic tissue and so on. Since the success of mission to the moon and construction of space station, the study on change of human physiological functions under microgravity has been underway. With the machine of microgravity developing maturely, associated researches have made big steps forward. However, intensive study on the changes of human hemostasis and thrombosis under the microgravity are still needed, especially in the area of high incidences of bleeding and thrombotic diseases. The result will help to prevent hemostasis and thrombosis on astronaut and promote the development of our national aerospace industry.