重症急性胰腺炎预测的早期相关因素临床分析

Clinical Analysis of Early Related Factors for Prediction of Severe Acute Pancreatitis

目的探讨预测急性胰腺炎病情轻重的早期相关因素。方法 428例急性胰腺炎患者按病情轻重分轻症组248例,重症组180例,回顾性分析入院24h内临床和实验室检查资料。结果轻症和重症两组患者比较,将有统计学意义的各观察指标经Logistic回归分析,预测急性胰腺炎病情严重度的相关因素依次为血钙>白细胞计数>血清白蛋白>肌酐>心率。血钙下降预测病情严重度最明显。结论血钙、白细胞计数、血清白蛋白、肌酐、心率可作为预测急性胰腺炎病情严重度相对独立的因素。

Objective To explore the early prognostic indexes associated with severity of acute pancreatitis. Methods All 428 cases of acute pancreatitis （ AP ） were divided in two groups, mild acute pancreatitis （ MAP ） 248 cases and severe acute pancreatitis （ SAP ） 180 cases. Clinical and laboratory＇ s data within 24 hours after admission of those patients were analyzed retrospectively. Results Within significant different indexes between MAP group and SAP group, blood calcium, blood lencocyte count, blood albumin, creatinine, heart rate were by turns prognostic indexes associated with severity of AP. by Logistic regression analysis, blood calcium alteration （ decrease ） was the most distinct prognostic index. Conclusion Blood calcium, blood lencocyte count, blood albumin, creatinine, heart rate are by turns prognostic indexes associated with severity of AP. These indexes above are independent prognostic indexes of SAP.