顽痹乐凝胶剂的制备与薄层色谱鉴别

Preparation and TLC Identification of Wanbile Gel

目的建立顽痹乐凝胶剂的制备工艺及质量控制方法。方法采用薄层色谱法对处方中主要药味祖师麻、白芍、当归、桂枝、秦艽、伸筋草进行定性鉴别。结果顽痹乐凝胶剂中的主要有效成分与相应对照品均有相同的鉴别反应,阴性对照品溶液色谱中无此斑点。结论该制剂工艺合理,薄层鉴别方法专属性强、重现性好,可作为该制剂质量控制方法之一。

Objective To establish the preparation technology and its quality control method for Wanbile Gel.Methods The main ingredients Daphne giraldii Nitsche,Radix Paeoniae Alba,Radix Angelicae Sinensis,Cortex Cinnamomi,Radix Gentianae Macrophyllae and Herba Lycopodiiin the formula were identified by thin layer chromatography（TLC）.Results Both the chief effective components of Wanbile Gel and the corresponding reference substances showed the identical discrimination reactions,however the characteristic dots were not shown in the negative control sample.Conclusion The preparation technology is proved to be rational and the TLC identification method is strongly sensitive with good reproducibility,which can be used for the quality control of Wanbile Gel.