血浆C-反应蛋白对肺动脉高压患者病情的评估价值被引量：1

THE VALUE OF SERUM C-REACTION PROTEIN IN ASSESSING THE SEVERITY OF PULMONARY ARTERY HYPERTENSION

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摘要目的探讨血浆C-反应蛋白对肺动脉高压患者病情的评估价值。方法收集116例确诊为肺动脉高压的患者及30例健康对照者,依据NYHA心功能分级,将肺动脉高压患者分为四组,比较各组患者平均肺动脉压、右心室收缩末期容量和射血分数,以及血浆C-反应蛋白和B-型利钠肽水平,同时进行Spearman秩相关分析血浆C-反应蛋白和B-型利钠肽水平与心功能的关系。结果①与健康对照组相比,肺动脉高压组患者平均肺动脉压和右心室收缩末期容量明显升高,而射血分数则明显降低(p<0.05);肺动脉高压患者随着NYHA心功能分级的加重,其平均肺动脉压和右心室收缩末期容量也逐渐则升高,而射血分数则逐渐降低;②肺动脉高压患者血浆C-反应蛋白和B-型利钠肽水平均不同程度升高,心功能Ⅳ级患者血浆C-反应蛋白和B-型利钠肽水平升高最明显(p<0.05)。Spearman秩相关分析结果提示肺动脉高压患者血浆C-反应蛋白和B-型利钠肽水平与心功能分级呈正相关,相关系数分别为r=0.894(p<0.05)和r=0.978(p<0.05)。结论肺动脉高压患者检测其血浆C-反应蛋白和B-型利钠肽水平,可以在一定程度上评估患者病情严重程度,具有一定的临床价值。

作者唐湘

机构地区广州市番禺区新造医院

出处《现代医院》 2011年第11期27-28,共2页 Modern Hospitals

关键词 C-反应蛋白 B-型利钠肽肺动脉高压

分类号 R654.2 [医药卫生—外科学]

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