肺炎支原体与C-反应蛋白同时检测在诊断小儿呼吸道感染中的价值

Diagnostic value of C-reactive protein and mycoplasma pneumonia antibody in infant respiratory tract infection

目的:探讨肺炎支原体、C-反应蛋白(CRP)同时检测在诊断小儿呼吸道感染中的价值。方法:对呼吸道感染患儿1 061例用被动凝集法检测肺炎支原体。其中,对肺炎支原体阳性(支原体肺炎组)121例、肺炎支原体阴性(细菌性肺炎组)50例和对照组30例健康儿童测定CRP。结果:1 061例小儿呼吸道感染患儿血清肺炎支原体阳性286例,阳性率为26.96%。支原体肺炎组CRP阳性35例,阳性率为28.93%,细菌性肺炎组CRP阳性47例,阳性率为94.00%,对照组CRP无一例阳性,三组比较,差异有高度统计学意义(P<0.01)。结论:支原体肺炎患儿CRP稍高但没有细菌性肺炎增高明显。肺炎支原体、CRP同时检测对支原体肺炎诊断和鉴别诊断有一定的临床意义。

Objective： To investigate the diagnostic value of C-reactive protein and mycoplasma pneumonia antibody in infant respiratory tract infection. Methods： 1 061 cases of respiratory tract infection in children were detected for my- coplasma prenmoniae antibody. There were 121 cases of positive MP （mycoplasma pueumonia group）, 50 cases of neg- ative MP （bacterial pueumonia group） and 30 cases of healthy children （control group）, and detected CRP in the three groups. Results： There were 286 cases of with positive serum MP in I 061 infants with respiratory tract infection, the pos- itive rate was 26.96%. There were 35 cases with positive serum CRP in mycoplasma pneumonia, the positive rate was 28.93%, and there were 47 cases with positive serum CRP in bacterial pneumonia, the positive rate was 94.00%, none of positive serum CRP in control group. There was a significant difference in the three groups （P〈0.01）. Conclusion： The incidence of positive serum CRP in mycoplasma pneumonia is significantly higher than that in bactecial pneumonia, the test of MP with CRP is of great value in diagnosing mycoplasma pneumonia and distinguishing it from other pneumonia.