1Stein M B. Public health perspectives on generalized anxiety disorder[J]. J Clin Psychiatry, 2004, 65 Suppl 13: 3-7.
2Cryan JF, Sweeney FF. The age of anxiety: role of animal models of anxiolytic action in drug discovery[J]. Br J Pharmacol, 2011, 164(4): 1129-1161.
3Pellow S, Chopin P, File SE, et al. Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat[J]. JNeurosciMethods, 1985, 14(3): 149-167.
4Cruz APM, Frei F, Graeff FG. Ethopharmacological analysis of rat behavior on the elevated plus-maze[J]. Pharmacol Biochem Behav, 1994, 49(1): 171-176.
5Lister RG. The use of a plus-maze to measure anxiety in the mouse[J]. Psychopharmacology(Berl), 1987, 92(2): 180-185.
6Lorenzini CA, Bucherelli C, Giachetti A. Passive and active avoidance behavior in the light-dark box test[J]. Physiol Behav, 1984, 32(4): 687-689.
7Crawley J, Goodwin FK. Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines[J]. PharmacolBiochemBehav, 1980, 13(2): 167-170.
8Costall B, Jones B J, Kelly ME, et al. Exploration of mice in a black and white test box: Validation as a model of anxiety[J]. PharmacolBiochem Behav, 1989, 32(3): 777-785.
9Miller SM, Piasecki CC, Lonstein JS. Use of the light-dark box to compare the anxiety-related behavior of virgin and postpartum female rats[J]. PharmacolBiochem Behav, 2011, 100(1): 130- 137.
10Bilkei-Gorzo A, Gyertyan I, Levay G. mCPP-induced anxiety in the light-dark box in rats--a new method for screening anxiolytic activity[J]. Psychopharmacology (Berl), 1998, 136(3): 291- 298.
9Luyten L, Vansteenwegen D, van Kuyck K, et al. Contextual con-ditioning in rats as an animal model for generalized anxiety disor- der[ J ]. Cognitive, affective, & behavioral neuroscience, 2011,11 (2) :228-244.
10Pellow S, Chopin P. Validation of open-closed arm entries in an elevated plus-maze as a measure of anxiety in the rat[J] .J Neu- rosci Methods, 1985,14(3) : 149-167.
